Daily Papers

We investigate whether methods of human mathematics pedagogy can guide the training of language models toward arithmetic reasoning. Building on the GASING method -- an Indonesian pedagogy that solves basic arithmetic through a left-to-right procedure aligned with the causal order of token generation -- we operationalize each operation as a computational procedure whose execution trace is serialized into natural-language Chain-of-Thought (CoT) supervision. A small GPT-2 decoder (86M parameters) with a syllabic-agglutinative TOBA tokenizer for Indonesian is trained from scratch on this data using only a next-token prediction objective, without reinforcement learning or reward-based optimization. Monitoring training reveals three distinct learning phases, and mechanistic analyses -- attention-masking interventions on the CoT information graph, residual-stream probing, and logit-lens inspection -- show that the model first internalizes a procedural pathway and subsequently develops an associative, ``mental-arithmetic'' capacity that retrieves intermediate results without explicit step-by-step computation. The trained model reaches over 80% accuracy on held-out problems and attains competitive performance against substantially larger language models, indicating that targeted, pedagogically grounded training can yield strong and economical arithmetic capability at small scale.

Multimodal generative models have made significant strides in image editing, demonstrating impressive performance on a variety of static tasks. However, their proficiency typically does not extend to complex scenarios requiring dynamic reasoning, leaving them ill-equipped to model the coherent, intermediate logical pathways that constitute a multi-step evolution from an initial state to a final one. This capacity is crucial for unlocking a deeper level of procedural and causal understanding in visual manipulation. To systematically measure this critical limitation, we introduce InEdit-Bench, the first evaluation benchmark dedicated to reasoning over intermediate pathways in image editing. InEdit-Bench comprises meticulously annotated test cases covering four fundamental task categories: state transition, dynamic process, temporal sequence, and scientific simulation. Additionally, to enable fine-grained evaluation, we propose a set of assessment criteria to evaluate the logical coherence and visual naturalness of the generated pathways, as well as the model's fidelity to specified path constraints. Our comprehensive evaluation of 14 representative image editing models on InEdit-Bench reveals significant and widespread shortcomings in this domain. By providing a standardized and challenging benchmark, we aim for InEdit-Bench to catalyze research and steer development towards more dynamic, reason-aware, and intelligent multimodal generative models.

Procedural memory enables large language model (LLM) agents to internalize "how-to" knowledge, theoretically reducing redundant trial-and-error. However, existing frameworks predominantly suffer from a "passive accumulation" paradigm, treating memory as a static append-only archive. To bridge the gap between static storage and dynamic reasoning, we propose ReMe (Remember Me, Refine Me), a comprehensive framework for experience-driven agent evolution. ReMe innovates across the memory lifecycle via three mechanisms: 1) multi-faceted distillation, which extracts fine-grained experiences by recognizing success patterns, analyzing failure triggers and generating comparative insights; 2) context-adaptive reuse, which tailors historical insights to new contexts via scenario-aware indexing; and 3) utility-based refinement, which autonomously adds valid memories and prunes outdated ones to maintain a compact, high-quality experience pool. Extensive experiments on BFCL-V3 and AppWorld demonstrate that ReMe establishes a new state-of-the-art in agent memory system. Crucially, we observe a significant memory-scaling effect: Qwen3-8B equipped with ReMe outperforms larger, memoryless Qwen3-14B, suggesting that self-evolving memory provides a computation-efficient pathway for lifelong learning. We release our code and the reme.library dataset to facilitate further research.

Following step-by-step procedures is an essential component of various activities carried out by individuals in their daily lives. These procedures serve as a guiding framework that helps to achieve goals efficiently, whether it is assembling furniture or preparing a recipe. However, the complexity and duration of procedural activities inherently increase the likelihood of making errors. Understanding such procedural activities from a sequence of frames is a challenging task that demands an accurate interpretation of visual information and the ability to reason about the structure of the activity. To this end, we collect a new egocentric 4D dataset, CaptainCook4D, comprising 384 recordings (94.5 hours) of people performing recipes in real kitchen environments. This dataset consists of two distinct types of activity: one in which participants adhere to the provided recipe instructions and another in which they deviate and induce errors. We provide 5.3K step annotations and 10K fine-grained action annotations and benchmark the dataset for the following tasks: supervised error recognition, multistep localization, and procedure learning

Procedural planning aims to implement complex high-level goals by decomposition into sequential simpler low-level steps. Although procedural planning is a basic skill set for humans in daily life, it remains a challenge for large language models (LLMs) that lack a deep understanding of the cause-effect relations in procedures. Previous methods require manual exemplars to acquire procedural planning knowledge from LLMs in the zero-shot setting. However, such elicited pre-trained knowledge in LLMs induces spurious correlations between goals and steps, which impair the model generalization to unseen tasks. In contrast, this paper proposes a neuro-symbolic procedural PLANner (PLAN) that elicits procedural planning knowledge from the LLMs with commonsense-infused prompting. To mitigate spurious goal-step correlations, we use symbolic program executors on the latent procedural representations to formalize prompts from commonsense knowledge bases as a causal intervention toward the Structural Causal Model. Both automatic and human evaluations on WikiHow and RobotHow show the superiority of PLAN on procedural planning without further training or manual exemplars.

Procedural activities, ranging from routine cooking to complex surgical operations, are highly structured as a set of actions conducted in a specific temporal order. Despite their success on static images and short clips, current self-supervised learning methods often overlook the procedural nature that underpins such activities. We expose the lack of procedural awareness in current SSL methods with a motivating experiment: models pretrained on forward and time-reversed sequences produce highly similar features, confirming that their representations are blind to the underlying procedural order. To address this shortcoming, we propose PL-Stitch, a self-supervised framework that harnesses the inherent temporal order of video frames as a powerful supervisory signal. Our approach integrates two novel probabilistic objectives based on the Plackett-Luce (PL) model. The primary PL objective trains the model to sort sampled frames chronologically, compelling it to learn the global workflow progression. The secondary objective, a spatio-temporal jigsaw loss, complements the learning by capturing fine-grained, cross-frame object correlations. Our approach consistently achieves superior performance across five surgical and cooking benchmarks. Specifically, PL-Stitch yields significant gains in surgical phase recognition (e.g., +11.4 pp k-NN accuracy on Cholec80) and cooking action segmentation (e.g., +5.7 pp linear probing accuracy on Breakfast), demonstrating its effectiveness for procedural video representation learning.

Online resources such as WikiHow compile a wide range of scripts for performing everyday tasks, which can assist models in learning to reason about procedures. However, the scripts are always presented in a linear manner, which does not reflect the flexibility displayed by people executing tasks in real life. For example, in the CrossTask Dataset, 64.5% of consecutive step pairs are also observed in the reverse order, suggesting their ordering is not fixed. In addition, each step has an average of 2.56 frequent next steps, demonstrating "branching". In this paper, we propose the new challenging task of non-sequential graph script induction, aiming to capture optional and interchangeable steps in procedural planning. To automate the induction of such graph scripts for given tasks, we propose to take advantage of loosely aligned videos of people performing the tasks. In particular, we design a multimodal framework to ground procedural videos to WikiHow textual steps and thus transform each video into an observed step path on the latent ground truth graph script. This key transformation enables us to train a script knowledge model capable of both generating explicit graph scripts for learnt tasks and predicting future steps given a partial step sequence. Our best model outperforms the strongest pure text/vision baselines by 17.52% absolute gains on F1@3 for next step prediction and 13.8% absolute gains on Acc@1 for partial sequence completion. Human evaluation shows our model outperforming the WikiHow linear baseline by 48.76% absolute gains in capturing sequential and non-sequential step relationships.

Procedural planning aims to predict a sequence of actions that transforms an initial visual state into a desired goal, a fundamental ability for intelligent agents operating in complex environments. Existing approaches typically rely on large-scale models that learn procedural structures implicitly, resulting in limited sample-efficiency and high computational cost. In this work we introduce ViterbiPlanNet, a principled framework that explicitly integrates procedural knowledge into the learning process through a Differentiable Viterbi Layer (DVL). The DVL embeds a Procedural Knowledge Graph (PKG) directly with the Viterbi decoding algorithm, replacing non-differentiable operations with smooth relaxations that enable end-to-end optimization. This design allows the model to learn through graph-based decoding. Experiments on CrossTask, COIN, and NIV demonstrate that ViterbiPlanNet achieves state-of-the-art performance with an order of magnitude fewer parameters than diffusion- and LLM-based planners. Extensive ablations show that performance gains arise from our differentiable structure-aware training rather than post-hoc refinement, resulting in improved sample efficiency and robustness to shorter unseen horizons. We also address testing inconsistencies establishing a unified testing protocol with consistent splits and evaluation metrics. With this new protocol, we run experiments multiple times and report results using bootstrapping to assess statistical significance.

Understanding procedural natural language (e.g., step-by-step instructions) is a crucial step to execution and planning. However, while there are ample corpora and downstream tasks available in English, the field lacks such resources for most languages. To address this gap, we conduct a case study on Turkish procedural texts. We first expand the number of tutorials in Turkish wikiHow from 2,000 to 52,000 using automated translation tools, where the translation quality and loyalty to the original meaning are validated by a team of experts on a random set. Then, we generate several downstream tasks on the corpus, such as linking actions, goal inference, and summarization. To tackle these tasks, we implement strong baseline models via fine-tuning large language-specific models such as TR-BART and BERTurk, as well as multilingual models such as mBART, mT5, and XLM. We find that language-specific models consistently outperform their multilingual models by a significant margin across most procedural language understanding (PLU) tasks. We release our corpus, downstream tasks and the baseline models with https://github.com/ GGLAB-KU/turkish-plu.

In this paper we present an approach for localizing steps of procedural activities in narrated how-to videos. To deal with the scarcity of labeled data at scale, we source the step descriptions from a language knowledge base (wikiHow) containing instructional articles for a large variety of procedural tasks. Without any form of manual supervision, our model learns to temporally ground the steps of procedural articles in how-to videos by matching three modalities: frames, narrations, and step descriptions. Specifically, our method aligns steps to video by fusing information from two distinct pathways: i) {\em direct} alignment of step descriptions to frames, ii) {\em indirect} alignment obtained by composing steps-to-narrations with narrations-to-video correspondences. Notably, our approach performs global temporal grounding of all steps in an article at once by exploiting order information, and is trained with step pseudo-labels which are iteratively refined and aggressively filtered. In order to validate our model we introduce a new evaluation benchmark -- HT-Step -- obtained by manually annotating a 124-hour subset of HowTo100MA test server is accessible at \url{https://eval.ai/web/challenges/challenge-page/2082.} with steps sourced from wikiHow articles. Experiments on this benchmark as well as zero-shot evaluations on CrossTask demonstrate that our multi-modality alignment yields dramatic gains over several baselines and prior works. Finally, we show that our inner module for matching narration-to-video outperforms by a large margin the state of the art on the HTM-Align narration-video alignment benchmark.

A hallmark of human intelligence is the ability to create complex artifacts through structured multi-step processes. Generating procedural tutorials with AI is a longstanding but challenging goal, facing three key obstacles: (1) scarcity of multi-task procedural datasets, (2) maintaining logical continuity and visual consistency between steps, and (3) generalizing across multiple domains. To address these challenges, we propose a multi-domain dataset covering 21 tasks with over 24,000 procedural sequences. Building upon this foundation, we introduce MakeAnything, a framework based on the diffusion transformer (DIT), which leverages fine-tuning to activate the in-context capabilities of DIT for generating consistent procedural sequences. We introduce asymmetric low-rank adaptation (LoRA) for image generation, which balances generalization capabilities and task-specific performance by freezing encoder parameters while adaptively tuning decoder layers. Additionally, our ReCraft model enables image-to-process generation through spatiotemporal consistency constraints, allowing static images to be decomposed into plausible creation sequences. Extensive experiments demonstrate that MakeAnything surpasses existing methods, setting new performance benchmarks for procedural generation tasks.

Medical care follows complex clinical pathways that extend beyond isolated physician-patient encounters, emphasizing decision-making and transitions between different stages. Current benchmarks focusing on static exams or isolated dialogues inadequately evaluate large language models (LLMs) in dynamic clinical scenarios. We introduce CP-Env, a controllable agentic hospital environment designed to evaluate LLMs across end-to-end clinical pathways. CP-Env simulates a hospital ecosystem with patient and physician agents, constructing scenarios ranging from triage and specialist consultation to diagnostic testing and multidisciplinary team meetings for agent interaction. Following real hospital adaptive flow of healthcare, it enables branching, long-horizon task execution. We propose a three-tiered evaluation framework encompassing Clinical Efficacy, Process Competency, and Professional Ethics. Results reveal that most models struggle with pathway complexity, exhibiting hallucinations and losing critical diagnostic details. Interestingly, excessive reasoning steps can sometimes prove counterproductive, while top models tend to exhibit reduced tool dependency through internalized knowledge. CP-Env advances medical AI agents development through comprehensive end-to-end clinical evaluation. We provide the benchmark and evaluation tools for further research and development at https://github.com/SPIRAL-MED/CP_ENV.

Despite the rapid progress of Multimodal Large Language Models (MLLMs), their ability to perform reliable visual grounding in high-stakes clinical software environments remains underexplored. Existing GUI benchmarks largely focus on isolated, single-step grounding queries, overlooking the sequential, workflow-driven reasoning required in real-world medical interfaces, where tasks evolve across independent steps and dynamic interface states. We introduce MedSPOT, a workflow-aware sequential grounding benchmark for clinical GUI environments. Unlike prior benchmarks that treat grounding as a standalone prediction task, MedSPOT models procedural interaction as a sequence of structured spatial decisions. The benchmark comprises 216 task-driven videos with 597 annotated keyframes, in which each task consists of 2 to 3 interdependent grounding steps within realistic medical workflows. This design captures interface hierarchies, contextual dependencies, and fine-grained spatial precision under evolving conditions. To evaluate procedural robustness, we propose a strict sequential evaluation protocol that terminates task assessment upon the first incorrect grounding prediction, explicitly measuring error propagation in multi-step workflows. We further introduce a comprehensive failure taxonomy, including edge bias, small-target errors, no prediction, near miss, far miss, and toolbar confusion, to enable systematic diagnosis of model behavior in clinical GUI settings. By shifting evaluation from isolated grounding to workflow-aware sequential reasoning, MedSPOT establishes a realistic and safety-critical benchmark for assessing multimodal models in medical software environments. Code and data are available at: https://github.com/Tajamul21/MedSPOT.

Biological protocols are fundamental to reproducible and safe life science research. While LLMs excel on general tasks, their systematic evaluation on these highly specialized, accuracy-critical, and inherently procedural texts remains limited. In this work, we present BioProBench, the first large-scale, integrated multi-task benchmark for biological protocol understanding and reasoning. While limited benchmarks have touched upon specific aspects like protocol QA, BioProBench provides a comprehensive suite of five core tasks: Protocol Question Answering, Step Ordering, Error Correction, Protocol Generation, and Protocol Reasoning, enabling a holistic evaluation of LLMs on procedural biological texts. Built upon 27K original protocols, it yields nearly 556K high-quality structured instances. We evaluate 12 mainstream open/closed-source LLMs on BioProBench. Experimental results reveal that while top models preform well on surface understanding tasks, struggle significantly with deep reasoning and structured generation tasks like ordering and generation. Furthermore, model comparisons reveal diverse performance: certain open-source models approach closed-source levels on some tasks, yet bio-specific small models lag behind general LLMs, indicating limitations on complex procedural content. Overall, our findings underscore that procedural reasoning within biological protocols represents a significant challenge for current LLMs. BioProBench serves as a standardized framework to diagnose these specific limitations and guide the development of AI systems better equipped for safely automating complex scientific procedures. The code and data are available at: https://github.com/YuyangSunshine/bioprotocolbench and https://huggingface.co/datasets/GreatCaptainNemo/BioProBench.

Procedural text describes dynamic state changes during a step-by-step natural process (e.g., photosynthesis). In this work, we focus on the task of procedural text understanding, which aims to comprehend such documents and track entities' states and locations during a process. Although recent approaches have achieved substantial progress, their results are far behind human performance. Two challenges, the difficulty of commonsense reasoning and data insufficiency, still remain unsolved, which require the incorporation of external knowledge bases. Previous works on external knowledge injection usually rely on noisy web mining tools and heuristic rules with limited applicable scenarios. In this paper, we propose a novel KnOwledge-Aware proceduraL text understAnding (KOALA) model, which effectively leverages multiple forms of external knowledge in this task. Specifically, we retrieve informative knowledge triples from ConceptNet and perform knowledge-aware reasoning while tracking the entities. Besides, we employ a multi-stage training schema which fine-tunes the BERT model over unlabeled data collected from Wikipedia before further fine-tuning it on the final model. Experimental results on two procedural text datasets, ProPara and Recipes, verify the effectiveness of the proposed methods, in which our model achieves state-of-the-art performance in comparison to various baselines.

Test-time scaling has emerged as an effective way to improve language models on challenging reasoning tasks. However, most existing methods treat each problem in isolation and do not systematically reuse knowledge from prior reasoning trajectories. In particular, they underutilize procedural knowledge: how to reframe a problem, choose an approach, and verify or backtrack when needed. We introduce Reasoning Memory, a retrieval-augmented generation (RAG) framework for reasoning models that explicitly retrieves and reuses procedural knowledge at scale. Starting from existing corpora of step-by-step reasoning trajectories, we decompose each trajectory into self-contained subquestion-subroutine pairs, yielding a datastore of 32 million compact procedural knowledge entries. At inference time, a lightweight in-thought prompt lets the model verbalize the core subquestion, retrieve relevant subroutines within its reasoning trace, and reason under diverse retrieved subroutines as implicit procedural priors. Across six math, science, and coding benchmarks, Reasoning Memory consistently outperforms RAG with document, trajectory, and template knowledge, as well as a compute-matched test-time scaling baseline. With a higher inference budget, it improves over no retrieval by up to 19.2% and over the strongest compute-matched baseline by 7.9% across task types. Ablation studies show that these gains come from two key factors: the broad procedural coverage of the source trajectories and our decomposition and retrieval design, which together enable effective extraction and reuse of procedural knowledge.

Generating step-by-step "how-to" procedures is a key LLM capability: how-to advice is commonly requested in chatbots, and step-by-step planning is critical for reasoning over complex tasks. Yet, measuring and improving procedural validity at scale on real-world tasks remains challenging and understudied. To address this, we introduce How2Everything, a scalable framework to evaluate and improve goal-conditioned procedure generation. Our framework includes How2Mine, which mines 351K procedures from 980K web pages across 14 topics and readily scales to larger corpora. From this pool we build How2Bench, a 7K-example evaluation set balanced across topics. To reliably score model outputs, we develop How2Score, an evaluation protocol that uses an LLM judge to detect whether a generation contains any critical failure that would prevent achieving the goal. For low-cost, reproducible evaluation, we distill a frontier model into an open 8B model, achieving 80.5% agreement with human annotators. How2Bench reveals clear scaling trends across model sizes and training stages, providing signal early in pretraining. Finally, RL using How2Score as a reward improves performance on How2Bench by >10 points across three models without systematic regressions on standard benchmarks, with gains robust to superficial source-document memorization or format compliance. Taken together, How2Everything shows how pretraining web data can support a closed loop of capability evaluation and improvement at scale.

Research on autonomous surgery has largely focused on simple task automation in controlled environments. However, real-world surgical applications demand dexterous manipulation over extended durations and generalization to the inherent variability of human tissue. These challenges remain difficult to address using existing logic-based or conventional end-to-end learning approaches. To address this gap, we propose a hierarchical framework for performing dexterous, long-horizon surgical steps. Our approach utilizes a high-level policy for task planning and a low-level policy for generating robot trajectories. The high-level planner plans in language space, generating task-level or corrective instructions that guide the robot through the long-horizon steps and correct for the low-level policy's errors. We validate our framework through ex vivo experiments on cholecystectomy, a commonly-practiced minimally invasive procedure, and conduct ablation studies to evaluate key components of the system. Our method achieves a 100\% success rate across eight unseen ex vivo gallbladders, operating fully autonomously without human intervention. This work demonstrates step-level autonomy in a surgical procedure, marking a milestone toward clinical deployment of autonomous surgical systems.

Cardiovascular diseases (CVDs) remain the leading cause of mortality globally, and echocardiography is critical for diagnosis of both common and congenital cardiac conditions. However, echocardiographic data for certain pathologies are scarce, hindering the development of robust automated diagnosis models. In this work, we propose Echo-Path, a novel generative framework to produce echocardiogram videos conditioned on specific cardiac pathologies. Echo-Path can synthesize realistic ultrasound video sequences that exhibit targeted abnormalities, focusing here on atrial septal defect (ASD) and pulmonary arterial hypertension (PAH). Our approach introduces a pathology-conditioning mechanism into a state-of-the-art echo video generator, allowing the model to learn and control disease-specific structural and motion patterns in the heart. Quantitative evaluation demonstrates that the synthetic videos achieve low distribution distances, indicating high visual fidelity. Clinically, the generated echoes exhibit plausible pathology markers. Furthermore, classifiers trained on our synthetic data generalize well to real data and, when used to augment real training sets, it improves downstream diagnosis of ASD and PAH by 7\% and 8\% respectively. Code, weights and dataset are available here https://github.com/Marshall-mk/EchoPathv1

Procedural planning, which entails decomposing a high-level goal into a sequence of temporally ordered steps, is an important yet intricate task for machines. It involves integrating common-sense knowledge to reason about complex contextualized situations that are often counterfactual, e.g. "scheduling a doctor's appointment without a phone". While current approaches show encouraging results using large language models (LLMs), they are hindered by drawbacks such as costly API calls and reproducibility issues. In this paper, we advocate planning using smaller language models. We present PlaSma, a novel two-pronged approach to endow small language models with procedural knowledge and (counterfactual) planning capabilities. More concretely, we develop symbolic procedural knowledge distillation to enhance the implicit knowledge in small language models and an inference-time algorithm to facilitate more structured and accurate reasoning. In addition, we introduce a novel task, Counterfactual Planning, that requires a revision of a plan to cope with a counterfactual situation. In both the original and counterfactual setting, we show that orders-of-magnitude smaller models (770M-11B parameters) can compete and often surpass their larger teacher models' capabilities.

Embodied agents have achieved prominent performance in following human instructions to complete tasks. However, the potential of providing instructions informed by texts and images to assist humans in completing tasks remains underexplored. To uncover this capability, we present the multimodal procedural planning (MPP) task, in which models are given a high-level goal and generate plans of paired text-image steps, providing more complementary and informative guidance than unimodal plans. The key challenges of MPP are to ensure the informativeness, temporal coherence,and accuracy of plans across modalities. To tackle this, we propose Text-Image Prompting (TIP), a dual-modality prompting method that jointly leverages zero-shot reasoning ability in large language models (LLMs) and compelling text-to-image generation ability from diffusion-based models. TIP improves the interaction in the dual modalities using Text-to-Image Bridge and Image-to-Text Bridge, allowing LLMs to guide the textual-grounded image plan generation and leveraging the descriptions of image plans to ground the textual plan reversely. To address the lack of relevant datasets, we collect WIKIPLAN and RECIPEPLAN as a testbed for MPP. Our results show compelling human preferences and automatic scores against unimodal and multimodal baselines on WIKIPLAN and RECIPEPLAN in terms of informativeness, temporal coherence, and plan accuracy. Our code and data: https://github.com/YujieLu10/MPP.

This paper introduces Personalized Path Recourse, a novel method that generates recourse paths for an agent. The objective is to achieve desired goals (e.g., better outcomes compared to the agent's original paths of action), while ensuring a high similarity to the agent's original paths and being personalized to the agent. Personalization refers to the extent to which the new path is tailored to the agent's observed behavior patterns from their policy function. We train a personalized recourse agent to generate such personalized paths, which are obtained using reward functions that consider the goal, similarity, and personalization. The proposed method is applicable to both reinforcement learning and supervised learning settings for correcting or improving sequences of actions or sequences of data to achieve a pre-determined goal. The method is evaluated in various settings and demonstrates promising results.

Procedural Content Generation (PCG) algorithms provide a technique to generate complex and diverse environments in an automated way. However, while generating content with PCG methods is often straightforward, generating meaningful content that reflects specific intentions and constraints remains challenging. Furthermore, many PCG algorithms lack the ability to generate content in an open-ended manner. Recently, Large Language Models (LLMs) have shown to be incredibly effective in many diverse domains. These trained LLMs can be fine-tuned, re-using information and accelerating training for new tasks. In this work, we introduce MarioGPT, a fine-tuned GPT2 model trained to generate tile-based game levels, in our case Super Mario Bros levels. We show that MarioGPT can not only generate diverse levels, but can be text-prompted for controllable level generation, addressing one of the key challenges of current PCG techniques. As far as we know, MarioGPT is the first text-to-level model. We also combine MarioGPT with novelty search, enabling it to generate diverse levels with varying play-style dynamics (i.e. player paths). This combination allows for the open-ended generation of an increasingly diverse range of content.

Large language models (LLMs) often struggle when performing agentic tasks without substantial tool support, prom-pt engineering, or fine tuning. Despite research showing that domain-dependent, procedural knowledge can dramatically increase planning efficiency, little work evaluates its potential for improving LLM performance on agentic tasks that may require implicit planning. We formalize, implement, and evaluate an agentic LLM workflow that leverages procedural knowledge in the form of a hierarchical task network (HTN). Empirical results of our implementation show that hand-coded HTNs can dramatically improve LLM performance on agentic tasks, and using HTNs can boost a 20b or 70b parameter LLM to outperform a much larger 120b parameter LLM baseline. Furthermore, LLM-created HTNs improve overall performance, though less so. The results suggest that leveraging expertise--from humans, documents, or LLMs--to curate procedural knowledge will become another important tool for improving LLM workflows.

In this paper, we introduce a new process prejudge strategy in LLM reasoning to demonstrate that bootstrapping with process prejudge allows the LLM to adaptively anticipate the errors encountered when advancing the subsequent reasoning steps, similar to people sometimes pausing to think about what mistakes may occur and how to avoid them, rather than relying solely on trial and error. Specifically, we define a prejudge node in the rationale, which represents a reasoning step, with at least one step that follows the prejudge node that has no paths toward the correct answer. To synthesize the prejudge reasoning process, we present an automated reasoning framework with a dynamic tree-searching strategy. This framework requires only one LLM to perform answer judging, response critiquing, prejudge generation, and thought completion. Furthermore, we develop a two-phase training mechanism with supervised fine-tuning (SFT) and reinforcement learning (RL) to further enhance the reasoning capabilities of LLMs. Experimental results from competition-level complex reasoning demonstrate that our method can teach the model to prejudge before thinking and significantly enhance the reasoning ability of LLMs. Code and data is released at https://github.com/wjn1996/Prejudge-Before-Think.

Abundant procedural knowledge on the Web holds great potential for helping agents solve long-horizon tasks. However, such knowledge is often multimodal, heterogeneous, noisy, and implicitly assumes human executors, making it difficult to use directly as the skills required by agents. To bridge the gap between human-oriented guides and agent-executable skills, we formalize this problem as guide-to-skill learning: converting in-the-wild guides into executable skills and continuously improving them from trajectories observable to the agent. To evaluate the capability of existing agents on this task, we introduce MMG2Skill-Bench, the first benchmark designed for this problem. We further propose MMG2Skill, a closed-loop framework that compiles guides into editable skills, conditions a fixed vision-language model (VLM) agent on these skills during execution, and revises the skills from trajectory-level root-cause feedback without using benchmark scores. Across GUI control, open-ended gameplay, and strategic card play with six VLM backbones, MMG2Skill consistently outperforms vanilla baseline agents in every model-domain setting, achieving macro-average gains of +12.8 to +25.3 percentage points across backbones. Ablation studies show that directly prompting agents with raw guides can degrade performance, while both structured skill construction and trajectory-driven revision are necessary for the observed improvements. On success-inferable tasks, analyzer-based early stopping further prevents late-stage performance regressions and saves 25%-53% of attempts when the success signal is properly calibrated.

Procedural videos, exemplified by recipe demonstrations, are instrumental in conveying step-by-step instructions. However, understanding such videos is challenging as it involves the precise localization of steps and the generation of textual instructions. Manually annotating steps and writing instructions is costly, which limits the size of current datasets and hinders effective learning. Leveraging large but noisy video-transcript datasets for pre-training can boost performance but demands significant computational resources. Furthermore, transcripts contain irrelevant content and differ in style from human-written instructions. To mitigate these issues, we propose a novel technique, Sieve-&-Swap, to automatically generate high-quality training data for the recipe domain: (i) Sieve: filters irrelevant transcripts and (ii) Swap: acquires high-quality text by replacing transcripts with human-written instruction from a text-only recipe dataset. The resulting dataset is three orders of magnitude smaller than current web-scale datasets but enables efficient training of large-scale models. Alongside Sieve-&-Swap, we propose Procedure Transformer (ProcX), a model for end-to-end step localization and instruction generation for procedural videos. When pre-trained on our curated dataset, this model achieves state-of-the-art performance on YouCook2 and Tasty while using a fraction of the training data. We have released code and dataset.

The web is full of guidance on a wide variety of tasks, from changing the oil in your car to baking an apple pie. However, as content is created independently, a single task could have thousands of corresponding procedural texts. This makes it difficult for users to view the bigger picture and understand the multiple ways the task could be accomplished. In this work we propose an unsupervised learning approach for summarizing multiple procedural texts into an intuitive graph representation, allowing users to easily explore commonalities and differences. We demonstrate our approach on recipes, a prominent example of procedural texts. User studies show that our representation is intuitive and coherent and that it has the potential to help users with several sensemaking tasks, including adapting recipes for a novice cook and finding creative ways to spice up a dish.

This paper introduces Opus, a novel framework for generating and optimizing Workflows tailored to complex Business Process Outsourcing (BPO) use cases, focusing on cost reduction and quality enhancement while adhering to established industry processes and operational constraints. Our approach generates executable Workflows from Intention, defined as the alignment of Client Input, Client Output, and Process Context. These Workflows are represented as Directed Acyclic Graphs (DAGs), with nodes as Tasks consisting of sequences of executable Instructions, including tools and human expert reviews. We adopt a two-phase methodology: Workflow Generation and Workflow Optimization. In the Generation phase, Workflows are generated using a Large Work Model (LWM) informed by a Work Knowledge Graph (WKG) that encodes domain-specific procedural and operational knowledge. In the Optimization phase, Workflows are transformed into Workflow Graphs (WFGs), where optimal Workflows are determined through path optimization. Our experiments demonstrate that state-of-the-art Large Language Models (LLMs) face challenges in reliably retrieving detailed process data as well as generating industry-compliant workflows. The key contributions of this paper include: - The integration of a Work Knowledge Graph (WKG) into a Large Work Model (LWM), enabling the generation of context-aware, semantically aligned, structured and auditable Workflows. - A two-phase approach that combines Workflow Generation from Intention with graph-based Workflow Optimization. - Opus Alpha 1 Large and Opus Alpha 1 Small, models that outperform state-of-the-art LLMs by 38\% and 29\% respectively in Workflow Generation for a Medical Coding use case.

Procedural materials, represented as functional node graphs, are ubiquitous in computer graphics for photorealistic material appearance design. They allow users to perform intuitive and precise editing to achieve desired visual appearances. However, creating a procedural material given an input image requires professional knowledge and significant effort. In this work, we leverage the ability to convert procedural materials into standard Python programs and fine-tune a large pre-trained vision-language model (VLM) to generate such programs from input images. To enable effective fine-tuning, we also contribute an open-source procedural material dataset and propose to perform program-level augmentation by prompting another pre-trained large language model (LLM). Through extensive evaluation, we show that our method outperforms previous methods on both synthetic and real-world examples.

Procedures are inherently hierarchical. To "make videos", one may need to "purchase a camera", which in turn may require one to "set a budget". While such hierarchical knowledge is critical for reasoning about complex procedures, most existing work has treated procedures as shallow structures without modeling the parent-child relation. In this work, we attempt to construct an open-domain hierarchical knowledge-base (KB) of procedures based on wikiHow, a website containing more than 110k instructional articles, each documenting the steps to carry out a complex procedure. To this end, we develop a simple and efficient method that links steps (e.g., "purchase a camera") in an article to other articles with similar goals (e.g., "how to choose a camera"), recursively constructing the KB. Our method significantly outperforms several strong baselines according to automatic evaluation, human judgment, and application to downstream tasks such as instructional video retrieval. A demo with partial data can be found at https://wikihow-hierarchy.github.io. The code and the data are at https://github.com/shuyanzhou/wikihow_hierarchy.

We address the problem of extracting key steps from unlabeled procedural videos, motivated by the potential of Augmented Reality (AR) headsets to revolutionize job training and performance. We decompose the problem into two steps: representation learning and key steps extraction. We propose a training objective, Bootstrapped Multi-Cue Contrastive (BMC2) loss to learn disciriminative representations for various steps without any labels. Different from prior works, we develop techniques to train a light-weight temporal module which uses off-the-shelf features for self supervision. Our approach can seamlessly leverage information from multiple cues like optical flow, depth or gaze to learn discriminative features for key-steps making it amenable for AR applications. We finally extract key steps via a tunable algorithm that clusters the representations and samples. We show significant improvements over prior works for the task of key step localization and phase classification. Qualitative results demonstrate that the extracted key steps are meaningful to succinctly represent various steps of the procedural tasks.

Reasoning is central to a wide range of intellectual activities, and while the capabilities of large language models (LLMs) continue to advance, their performance in reasoning tasks remains limited. The processes and mechanisms underlying reasoning are not yet fully understood, but key elements include path exploration, selection of relevant knowledge, and multi-step inference. Problems are solved through the synthesis of these components. In this paper, we propose a benchmark that focuses on a specific aspect of reasoning ability: the direct evaluation of multi-step inference. To this end, we design a special reasoning task where multi-step inference is specifically focused by largely eliminating path exploration and implicit knowledge utilization. Our dataset comprises pairs of explicit instructions and corresponding questions, where the procedures necessary for solving the questions are entirely detailed within the instructions. This setup allows models to solve problems solely by following the provided directives. By constructing problems that require varying numbers of steps to solve and evaluating responses at each step, we enable a thorough assessment of state-of-the-art LLMs' ability to follow instructions. To ensure the robustness of our evaluation, we include multiple distinct tasks. Furthermore, by comparing accuracy across tasks, utilizing step-aware metrics, and applying separately defined measures of complexity, we conduct experiments that offer insights into the capabilities and limitations of LLMs in reasoning tasks. Our findings have significant implications for the development of LLMs and highlight areas for future research in advancing their reasoning abilities. Our dataset is available at https://huggingface.co/datasets/ifujisawa/procbench and code at https://github.com/ifujisawa/proc-bench.

We present a fast algorithm for the design of smooth paths (or trajectories) that are constrained to lie in a collection of axis-aligned boxes. We consider the case where the number of these safe boxes is large, and basic preprocessing of them (such as finding their intersections) can be done offline. At runtime we quickly generate a smooth path between given initial and terminal positions. Our algorithm designs trajectories that are guaranteed to be safe at all times, and detects infeasibility whenever such a trajectory does not exist. Our algorithm is based on two subproblems that we can solve very efficiently: finding a shortest path in a weighted graph, and solving (multiple) convex optimal-control problems. We demonstrate the proposed path planner on large-scale numerical examples, and we provide an efficient open-source software implementation, fastpathplanning.

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the differential, and reserve molecular imaging (e.g., amyloid-PET) for cases that remain uncertain after standard evaluation. Consequently, patients are observed with heterogeneous and often incomplete modality subsets. However, most current AI models assume fixed data modalities as the model inputs. In this paper, we present BrainAnytime, a unified pretraining framework pretrained on 34,899 3D brain scans from five datasets that support brain image analysis under arbitrary modality availability spanning multi-sequence MRI and amyloid-PET. A single model accepts whatever imaging is available, from a lone T1 scan to a full multimodal workup. Pretraining learns structural-molecular correspondences between MRI and PET via cross-modal distillation (RCMD) and prioritizes disease-vulnerable anatomy via atlas-guided curriculum masking (PACM), all within a shared 3D masked autoencoder (Multi-MAE3D). Across four downstream tasks and five clinically motivated modality settings, BrainAnytime largely outperforms modality-specific models, missing-modality baselines, and large-scale brain MRI pretrained foundation models on most modality settings. Notably, it surpasses the strongest missing-modality baselines with relative improvements of 6.2% and 7.0% in average accuracy on CN vs. AD and CN vs. MCI classification, respectively. Code is available at https://github.com/SDH-Lab/BrainAnytime.

Procedural texts help AI enhance reasoning about context and action sequences. Transforming these into Semantic Role Labeling (SRL) improves understanding of individual steps by identifying predicate-argument structure like {verb,what,where/with}. Procedural instructions are highly elliptic, for instance, (i) add cucumber to the bowl and (ii) add sliced tomatoes, the second step's where argument is inferred from the context, referring to where the cucumber was placed. Prior SRL benchmarks often miss implicit arguments, leading to incomplete understanding. To address this, we introduce Implicit-VidSRL, a dataset that necessitates inferring implicit and explicit arguments from contextual information in multimodal cooking procedures. Our proposed dataset benchmarks multimodal models' contextual reasoning, requiring entity tracking through visual changes in recipes. We study recent multimodal LLMs and reveal that they struggle to predict implicit arguments of what and where/with from multi-modal procedural data given the verb. Lastly, we propose iSRL-Qwen2-VL, which achieves a 17% relative improvement in F1-score for what-implicit and a 14.7% for where/with-implicit semantic roles over GPT-4o.

We introduce ProtoPathway, an interpretable-by-design multimodal framework for cancer survival prediction that unifies whole slide imaging and transcriptomics through encoders producing biologically grounded representations on both sides of the fusion. On the histopathology side, K learnable morphological prototypes, trained end-to-end with the survival objective, serve as the slide representation itself: patches flow into prototype tokens via soft assignment, compressing variable-length patch sets into fixed task-adaptive tokens. On the genomic side, a bipartite graph neural network encodes gene expression within the Reactome pathway hierarchy, producing pathway embeddings that reflect both constituent genes and their broader biological context through bidirectional message passing over a shared gene--pathway graph. Cross-modal attention then operates over a compact prototype times pathway matrix in which prototypes query pathways, modeling the biological direction in which molecular programs give rise to tissue morphology. Because both axes carry stable task-learned identity, the attention matrix is itself an interpretability output, yielding native inference-time attribution across the full biological hierarchy, from genes through pathways and prototypes to spatial tissue maps. We evaluate on five TCGA cancer cohorts, demonstrating competitive or superior survival prediction with substantially improved biological interpretability and reduced computational cost, with interpretability claims validated through fold-stratified rank-based population-level analysis. Our source code, model weights, and Reactome pathways, together with a unified codebase reimplementing all multimodal survival baselines under identical preprocessing and evaluation, are available at: https://github.com/AmayaGS/ProtoPathway.

Chain-of-thought (CoT) reasoning has advanced medical visual question answering (VQA), yet most existing CoT rationales are free-form and fail to capture the structured reasoning process clinicians actually follow. This work asks: Can traceable, multi-step reasoning supervision improve reasoning accuracy and the interpretability of Medical VQA? To this end, we introduce Step-CoT, a large-scale medical reasoning dataset with expert-curated, structured multi-step CoT aligned to clinical diagnostic workflows, implicitly grounding the model's reasoning in radiographic evidence. Step-CoT comprises more than 10K real clinical cases and 70K VQA pairs organized around diagnostic workflows, providing supervised intermediate steps that guide models to follow valid reasoning trajectories. To effectively learn from Step-CoT, we further introduce a teacher-student framework with a dynamic graph-structured focusing mechanism that prioritizes diagnostically informative steps while filtering out less relevant contexts. Our experiments show that using Step-CoT can improve reasoning accuracy and interpretability. Benchmark: github.com/hahaha111111/Step-CoT. Dataset Card: huggingface.co/datasets/fl-15o/Step-CoT

Long-horizon robotic manipulation requires dense feedback that reflects how a task advances through its procedural stages, not merely whether the final outcome is successful. Existing reward models often rely on trajectory-level success labels or time-based interpolation, which can conflate elapsed time with true task progress and therefore fail to capture unfinished steps, stagnation, and failure states. We present ProcVLM, a progress-aware vision-language model that learns procedure-grounded progress as a dense reward signal for manipulation. Rather than deriving progress from terminal outcomes or temporal proxies, ProcVLM grounds progress estimation in procedural structure and intra-stage visual change, and further adopts a reasoning-before-estimation paradigm that infers the remaining atomic actions before estimating task progress. Specifically, we construct this supervision by synthesizing frame-level subtask-semantic annotations, assigning progress budgets according to subtask structure, and distributing each budget based on intra-subtask visual change. To train ProcVLM at scale, we build a standardized procedural supervision synthesis pipeline and construct ProcCorpus-60M from 30 embodied datasets with 60M annotated frames, from which we derive ProcVQA for procedure-aware pretraining, with progress estimation as the central task alongside action segmentation and future planning. Experiments on ProcVQA and reward-model benchmarks show that ProcVLM improves embodied procedural reasoning and yields more discriminative trajectory-internal progress estimates than representative baselines, supporting its use as a dense reward model for downstream reward-guided policy optimization. Project page: https://procvlm.github.io/

Healthcare automation is shaped by local procedures and organizational constraints, so agent capabilities rarely transfer unchanged across settings. Agent skills, self-contained directories that package reusable procedures for AI agents, are emerging as a procedural layer for adapting healthcare agents across diverse healthcare settings. We present the first empirical analysis of healthcare agent skills, drawing on 557 healthcare-related skills filtered from 58,159 public skills on ClawHub and annotated along ten dimensions covering function, deployment context, autonomy, and safety. We find that public healthcare skills emphasize patient-facing workflow automation and monitoring rather than the diagnostic and treatment-oriented tasks foregrounded in healthcare-agent research; coverage of the healthcare lifecycle and specialized clinical inputs remains uneven; and general technical risk does not reliably capture clinical risk. These findings position healthcare skills as a procedural layer not yet addressed by current benchmarks and risk frameworks.

We propose to improve transformers of a specific modality with irrelevant data from other modalities, e.g., improve an ImageNet model with audio or point cloud datasets. We would like to highlight that the data samples of the target modality are irrelevant to the other modalities, which distinguishes our method from other works utilizing paired (e.g., CLIP) or interleaved data of different modalities. We propose a methodology named Multimodal Pathway - given a target modality and a transformer designed for it, we use an auxiliary transformer trained with data of another modality and construct pathways to connect components of the two models so that data of the target modality can be processed by both models. In this way, we utilize the universal sequence-to-sequence modeling abilities of transformers obtained from two modalities. As a concrete implementation, we use a modality-specific tokenizer and task-specific head as usual but utilize the transformer blocks of the auxiliary model via a proposed method named Cross-Modal Re-parameterization, which exploits the auxiliary weights without any inference costs. On the image, point cloud, video, and audio recognition tasks, we observe significant and consistent performance improvements with irrelevant data from other modalities. The code and models are available at https://github.com/AILab-CVC/M2PT.

Understanding what sequence of steps are needed to complete a goal can help artificial intelligence systems reason about human activities. Past work in NLP has examined the task of goal-step inference for text. We introduce the visual analogue. We propose the Visual Goal-Step Inference (VGSI) task, where a model is given a textual goal and must choose which of four images represents a plausible step towards that goal. With a new dataset harvested from wikiHow consisting of 772,277 images representing human actions, we show that our task is challenging for state-of-the-art multimodal models. Moreover, the multimodal representation learned from our data can be effectively transferred to other datasets like HowTo100m, increasing the VGSI accuracy by 15 - 20%. Our task will facilitate multimodal reasoning about procedural events.

We present the design of a new large scale orchestration layer for accelerators. Our system, Pathways, is explicitly designed to enable exploration of new systems and ML research ideas, while retaining state of the art performance for current models. Pathways uses a sharded dataflow graph of asynchronous operators that consume and produce futures, and efficiently gang-schedules heterogeneous parallel computations on thousands of accelerators while coordinating data transfers over their dedicated interconnects. Pathways makes use of a novel asynchronous distributed dataflow design that lets the control plane execute in parallel despite dependencies in the data plane. This design, with careful engineering, allows Pathways to adopt a single-controller model that makes it easier to express complex new parallelism patterns. We demonstrate that Pathways can achieve performance parity (~100% accelerator utilization) with state-of-the-art systems when running SPMD computations over 2048 TPUs, while also delivering throughput comparable to the SPMD case for Transformer models that are pipelined across 16 stages, or sharded across two islands of accelerators connected over a data center network.

Terminal agents have demonstrated strong potential for autonomous command-line execution, yet their training remains constrained by the scarcity of high-quality and diverse execution trajectories. Existing approaches mitigate this bottleneck by synthesizing large-scale terminal task instances for trajectory sampling. However, they primarily focus on scaling the number of tasks while providing limited control over the diversity of execution trajectories that agents actually experience during training. In this paper, we present SkillSynth, an automated framework for terminal task synthesis built on a scenario-mediated skill graph. SkillSynth first constructs a large-scale skill graph, where scenarios serve as intermediate transition nodes that connect diverse command-line skills. It then samples paths from this graph as abstractions of real-world workflows, and uses a multi-agent harness to instantiate them into executable task instances. By grounding task synthesis in graph-sampled workflow paths, SkillSynth explicitly controls the diversity of minimal execution trajectories required to solve the synthesized tasks. Experiments on Terminal-Bench demonstrate the effectiveness of SkillSynth. Moreover, task instances synthesized by SkillSynth have been adopted to train Hy3 Preview, contributing to its enhanced agentic capabilities in terminal-based settings.

Biologically-informed neural networks typically leverage pathway annotations to enhance performance in biomedical applications. We hypothesized that the benefits of pathway integration does not arise from its biological relevance, but rather from the sparsity it introduces. We conducted a comprehensive analysis of all relevant pathway-based neural network models for predictive tasks, critically evaluating each study's contributions. From this review, we curated a subset of methods for which the source code was publicly available. The comparison of the biologically informed state-of-the-art deep learning models and their randomized counterparts showed that models based on randomized information performed equally well as biologically informed ones across different metrics and datasets. Notably, in 3 out of the 15 analyzed models, the randomized versions even outperformed their biologically informed counterparts. Moreover, pathway-informed models did not show any clear advantage in interpretability, as randomized models were still able to identify relevant disease biomarkers despite lacking explicit pathway information. Our findings suggest that pathway annotations may be too noisy or inadequately explored by current methods. Therefore, we propose a methodology that can be applied to different domains and can serve as a robust benchmark for systematically comparing novel pathway-informed models against their randomized counterparts. This approach enables researchers to rigorously determine whether observed performance improvements can be attributed to biological insights.

Skill assessment in procedural videos is crucial for the objective evaluation of human performance in settings such as manufacturing and procedural daily tasks. Current research on skill assessment has predominantly focused on sports and lacks large-scale datasets for complex procedural activities. Existing studies typically involve only a limited number of actions, focus on either pairwise assessments (e.g., A is better than B) or on binary labels (e.g., good execution vs needs improvement). In response to these shortcomings, we introduce ProSkill, the first benchmark dataset for action-level skill assessment in procedural tasks. ProSkill provides absolute skill assessment annotations, along with pairwise ones. This is enabled by a novel and scalable annotation protocol that allows for the creation of an absolute skill assessment ranking starting from pairwise assessments. This protocol leverages a Swiss Tournament scheme for efficient pairwise comparisons, which are then aggregated into consistent, continuous global scores using an ELO-based rating system. We use our dataset to benchmark the main state-of-the-art skill assessment algorithms, including both ranking-based and pairwise paradigms. The suboptimal results achieved by the current state-of-the-art highlight the challenges and thus the value of ProSkill in the context of skill assessment for procedural videos. All data and code are available at https://fpv-iplab.github.io/ProSkill/

Complex reasoning tasks often rely on the ability to consistently and accurately apply simple rules across incremental steps, a foundational capability which we term "level-0" reasoning. To systematically evaluate this capability, we introduce L0-Bench, a language model benchmark for testing procedural correctness -- the ability to generate correct reasoning processes, complementing existing benchmarks that primarily focus on outcome correctness. Given synthetic Python functions with simple operations, L0-Bench grades models on their ability to generate step-by-step, error-free execution traces. The synthetic nature of L0-Bench enables systematic and scalable generation of test programs along various axes (e.g., number of trace steps). We evaluate a diverse array of recent closed-source and open-weight models on a baseline test set. All models exhibit degradation as the number of target trace steps increases, while larger models and reasoning-enhanced models better maintain correctness over multiple steps. Additionally, we use L0-Bench to explore test-time scaling along three dimensions: input context length, number of solutions for majority voting, and inference steps. Our results suggest substantial room to improve "level-0" reasoning and potential directions to build more reliable reasoning systems.

In the game development process, creating character animations is a vital step that involves several stages. Typically for 2D games, illustrators begin by designing the main character image, which serves as the foundation for all subsequent animations. To create a smooth motion sequence, these subsequent animations involve drawing the character in different poses and actions, such as running, jumping, or attacking. This process requires significant manual effort from illustrators, as they must meticulously ensure consistency in design, proportions, and style across multiple motion frames. Each frame is drawn individually, making this a time-consuming and labor-intensive task. Generative models, such as diffusion models, have the potential to revolutionize this process by automating the creation of sprite sheets. Diffusion models, known for their ability to generate diverse images, can be adapted to create character animations. By leveraging the capabilities of diffusion models, we can significantly reduce the manual workload for illustrators, accelerate the animation creation process, and open up new creative possibilities in game development.

Human experience in digital environments offers a vast, underexplored resource of authentic, untrimmed interactions that contain rich procedural knowledge. We introduce Demo2Tutorial, a framework that transforms this experience captured via screen recordings and interaction logs into structured, multimodal software tutorials for teaching both humans and agents. Demo2Tutorial first collects human experience via a dedicated recorder, then parses raw experience using a multimodal Action Parser to reconstruct perception, action, and intent. A Step Planner then abstracts these steps into hierarchical task graphs representing goals and steps. Finally, a Tutorial Composer transforms the parsed experience into structured, reusable image-text instructions. We evaluate the tutorial generation quality on a new benchmark derived from official software documentation. We further demonstrate that this distilled representation benefits (i) human learning, by automatically generating multimodal tutorials, and (ii) agent learning, by improving downstream GUI-agent planning and generalization. Experiments show Demo2Tutorial produces high-quality tutorials that surpass human-authored ones and significantly outperform baseline methods, while enabling both faster human task completion and improved GUI agent planning, demonstrating that structured tutorials distilled from human experience can serve as effective knowledge representations for advancing both human learning and agent capabilities. Code and data will be available at https://github.com/showlab/Demo2Tutorial.

Understanding the abilities of LLMs to reason about natural language plans, such as instructional text and recipes, is critical to reliably using them in decision-making systems. A fundamental aspect of plans is the temporal order in which their steps needs to be executed, which reflects the underlying causal dependencies between them. We introduce CaT-Bench, a benchmark of Step Order Prediction questions, which test whether a step must necessarily occur before or after another in cooking recipe plans. We use this to evaluate how well frontier LLMs understand causal and temporal dependencies. We find that SOTA LLMs are underwhelming (best zero-shot is only 0.59 in F1), and are biased towards predicting dependence more often, perhaps relying on temporal order of steps as a heuristic. While prompting for explanations and using few-shot examples improve performance, the best F1 result is only 0.73. Further, human evaluation of explanations along with answer correctness show that, on average, humans do not agree with model reasoning. Surprisingly, we also find that explaining after answering leads to better performance than normal chain-of-thought prompting, and LLM answers are not consistent across questions about the same step pairs. Overall, results show that LLMs' ability to detect dependence between steps has significant room for improvement.

Reusable skills have become a core substrate for improving agent capabilities, yet most existing skill packages encode reusable behavior primarily as textual prompts, executable code, or learned routines. For visual agents, however, procedural knowledge is inherently multimodal: reuse depends not only on what operation to perform, but also on recognizing the relevant state, interpreting visual evidence of progress or failure, and deciding what to do next. We formalize this requirement as multimodal procedural knowledge and address three practical challenges: (I) what a multimodal skill package should contain; (II) where such packages can be derived from public interaction experience; and (III) how agents can consult multimodal evidence at inference time without excessive image context or over-anchoring to reference screenshots. We introduce MMSkills, a framework for representing, generating, and using reusable multimodal procedures for runtime visual decision making. Each MMSkill is a compact, state-conditioned package that couples a textual procedure with runtime state cards and multi-view keyframes. To construct these packages, we develop an agentic trajectory-to-skill Generator that transforms public non-evaluation trajectories into reusable multimodal skills through workflow grouping, procedure induction, visual grounding, and meta-skill-guided auditing. To use them, we introduce a branch-loaded multimodal skill agent: selected state cards and keyframes are inspected in a temporary branch, aligned with the live environment, and distilled into structured guidance for the main agent. Experiments across GUI and game-based visual-agent benchmarks show that MMSkills consistently improve both frontier and smaller multimodal agents, suggesting that external multimodal procedural knowledge complements model-internal priors.

Stepwise inference protocols, such as scratchpads and chain-of-thought, help language models solve complex problems by decomposing them into a sequence of simpler subproblems. Despite the significant gain in performance achieved via these protocols, the underlying mechanisms of stepwise inference have remained elusive. To address this, we propose to study autoregressive Transformer models on a synthetic task that embodies the multi-step nature of problems where stepwise inference is generally most useful. Specifically, we define a graph navigation problem wherein a model is tasked with traversing a path from a start to a goal node on the graph. Despite is simplicity, we find we can empirically reproduce and analyze several phenomena observed at scale: (i) the stepwise inference reasoning gap, the cause of which we find in the structure of the training data; (ii) a diversity-accuracy tradeoff in model generations as sampling temperature varies; (iii) a simplicity bias in the model's output; and (iv) compositional generalization and a primacy bias with in-context exemplars. Overall, our work introduces a grounded, synthetic framework for studying stepwise inference and offers mechanistic hypotheses that can lay the foundation for a deeper understanding of this phenomenon.

Agent Skills are structured packages of procedural knowledge that augment LLM agents at inference time. Despite rapid adoption, there is no standard way to measure whether they actually help. We present SkillsBench, a benchmark of 86 tasks across 11 domains paired with curated Skills and deterministic verifiers. Each task is evaluated under three conditions: no Skills, curated Skills, and self-generated Skills. We test 7 agent-model configurations over 7,308 trajectories. Curated Skills raise average pass rate by 16.2 percentage points(pp), but effects vary widely by domain (+4.5pp for Software Engineering to +51.9pp for Healthcare) and 16 of 84 tasks show negative deltas. Self-generated Skills provide no benefit on average, showing that models cannot reliably author the procedural knowledge they benefit from consuming. Focused Skills with 2--3 modules outperform comprehensive documentation, and smaller models with Skills can match larger models without them.

Unprecedented breakthroughs in Large Language Models (LLMs) has amplified its penetration into application of automated visualization code generation. Few-shot prompting and query expansion techniques have notably enhanced data visualization performance, however, still fail to overcome ambiguity and complexity of natural language queries - imposing an inherent burden for manual human intervention. To mitigate such limitations, we propose a holistic framework VisPath : A Multi-Path Reasoning and Feedback-Driven Optimization Framework for Visualization Code Generation, which systematically enhances code quality through structured reasoning and refinement. VisPath is a multi-stage framework, specially designed to handle underspecified queries. To generate a robust final visualization code, it first utilizes initial query to generate diverse reformulated queries via Chain-of-Thought (CoT) prompting, each representing a distinct reasoning path. Refined queries are used to produce candidate visualization scripts, consequently executed to generate multiple images. Comprehensively assessing correctness and quality of outputs, VisPath generates feedback for each image, which are then fed to aggregation module to generate optimal result. Extensive experiments on benchmarks including MatPlotBench and the Qwen-Agent Code Interpreter Benchmark show that VisPath significantly outperforms state-of-the-art (SOTA) methods, increased up to average 17%, offering a more reliable solution for AI-driven visualization code generation.

In the pursuit of efficient automated content creation, procedural generation, leveraging modifiable parameters and rule-based systems, emerges as a promising approach. Nonetheless, it could be a demanding endeavor, given its intricate nature necessitating a deep understanding of rules, algorithms, and parameters. To reduce workload, we introduce 3D-GPT, a framework utilizing large language models~(LLMs) for instruction-driven 3D modeling. 3D-GPT positions LLMs as proficient problem solvers, dissecting the procedural 3D modeling tasks into accessible segments and appointing the apt agent for each task. 3D-GPT integrates three core agents: the task dispatch agent, the conceptualization agent, and the modeling agent. They collaboratively achieve two objectives. First, it enhances concise initial scene descriptions, evolving them into detailed forms while dynamically adapting the text based on subsequent instructions. Second, it integrates procedural generation, extracting parameter values from enriched text to effortlessly interface with 3D software for asset creation. Our empirical investigations confirm that 3D-GPT not only interprets and executes instructions, delivering reliable results but also collaborates effectively with human designers. Furthermore, it seamlessly integrates with Blender, unlocking expanded manipulation possibilities. Our work highlights the potential of LLMs in 3D modeling, offering a basic framework for future advancements in scene generation and animation.

LLMs often exhibit Aha moments during reasoning, such as apparent self-correction following tokens like "Wait," yet their underlying mechanisms remain unclear. We introduce an information-theoretic framework that decomposes reasoning into procedural information and epistemic verbalization - the explicit externalization of uncertainty that supports downstream control actions. We show that purely procedural reasoning can become informationally stagnant, whereas epistemic verbalization enables continued information acquisition and is critical for achieving information sufficiency. Empirical results demonstrate that strong reasoning performance is driven by uncertainty externalization rather than specific surface tokens. Our framework unifies prior findings on Aha moments and post-training experiments, and offers insights for future reasoning model design.

Promptly identifying procedural errors from egocentric videos in an online setting is highly challenging and valuable for detecting mistakes as soon as they happen. This capability has a wide range of applications across various fields, such as manufacturing and healthcare. The nature of procedural mistakes is open-set since novel types of failures might occur, which calls for one-class classifiers trained on correctly executed procedures. However, no technique can currently detect open-set procedural mistakes online. We propose PREGO, the first online one-class classification model for mistake detection in PRocedural EGOcentric videos. PREGO is based on an online action recognition component to model the current action, and a symbolic reasoning module to predict the next actions. Mistake detection is performed by comparing the recognized current action with the expected future one. We evaluate PREGO on two procedural egocentric video datasets, Assembly101 and Epic-tent, which we adapt for online benchmarking of procedural mistake detection to establish suitable benchmarks, thus defining the Assembly101-O and Epic-tent-O datasets, respectively.

3D Visual Question-Answering (3D VQA) is pivotal for models to perceive the physical world and perform spatial reasoning. Answer-centric supervision is a commonly used training method for 3D VQA models. Many models that utilize this strategy have achieved promising results in 3D VQA tasks. However, the answer-centric approach only supervises the final output of models and allows models to develop reasoning pathways freely. The absence of supervision on the reasoning pathway enables the potential for developing superficial shortcuts through common patterns in question-answer pairs. Moreover, although slow-thinking methods advance large language models, they suffer from underthinking. To address these issues, we propose HCNQA, a 3D VQA model leveraging a hierarchical concentration narrowing supervision method. By mimicking the human process of gradually focusing from a broad area to specific objects while searching for answers, our method guides the model to perform three phases of concentration narrowing through hierarchical supervision. By supervising key checkpoints on a general reasoning pathway, our method can ensure the development of a rational and effective reasoning pathway. Extensive experimental results demonstrate that our method can effectively ensure that the model develops a rational reasoning pathway and performs better. The code is available at https://github.com/JianuoZhu/HCNQA.

We present CrochetBench, a benchmark for evaluating the ability of multimodal large language models to perform fine-grained, low-level procedural reasoning in the domain of crochet. Unlike prior benchmarks that focus on high-level description or visual question answering, CrochetBench shifts the emphasis from describing to doing: models are required to recognize stitches, select structurally appropriate instructions, and generate compilable crochet procedures. We adopt the CrochetPARADE DSL as our intermediate representation, enabling structural validation and functional evaluation via execution. The benchmark covers tasks including stitch classification, instruction grounding, and both natural language and image-to-DSL translation. Across all tasks, performance sharply declines as the evaluation shifts from surface-level similarity to executable correctness, exposing limitations in long-range symbolic reasoning and 3D-aware procedural synthesis. CrochetBench offers a new lens for assessing procedural competence in multimodal models and highlights the gap between surface-level understanding and executable precision in real-world creative domains. Code is available at https://github.com/Peiyu-Georgia-Li/crochetBench.

There are substantial instructional videos on the Internet, which provide us tutorials for completing various tasks. Existing instructional video datasets only focus on specific steps at the video level, lacking experiential guidelines at the task level, which can lead to beginners struggling to learn new tasks due to the lack of relevant experience. Moreover, the specific steps without guidelines are trivial and unsystematic, making it difficult to provide a clear tutorial. To address these problems, we present the GUIDE (Guideline-Guided) dataset, which contains 3.5K videos of 560 instructional tasks in 8 domains related to our daily life. Specifically, we annotate each instructional task with a guideline, representing a common pattern shared by all task-related videos. On this basis, we annotate systematic specific steps, including their associated guideline steps, specific step descriptions and timestamps. Our proposed benchmark consists of three sub-tasks to evaluate comprehension ability of models: (1) Step Captioning: models have to generate captions for specific steps from videos. (2) Guideline Summarization: models have to mine the common pattern in task-related videos and summarize a guideline from them. (3) Guideline-Guided Captioning: models have to generate captions for specific steps under the guide of guideline. We evaluate plenty of foundation models with GUIDE and perform in-depth analysis. Given the diversity and practicality of GUIDE, we believe that it can be used as a better benchmark for instructional video comprehension.

We introduce Reasoning Gym (RG), a library of reasoning environments for reinforcement learning with verifiable rewards. It provides over 100 data generators and verifiers spanning multiple domains including algebra, arithmetic, computation, cognition, geometry, graph theory, logic, and various common games. Its key innovation is the ability to generate virtually infinite training data with adjustable complexity, unlike most previous reasoning datasets, which are typically fixed. This procedural generation approach allows for continuous evaluation across varying difficulty levels. Our experimental results demonstrate the efficacy of RG in both evaluating and reinforcement learning of reasoning models.

Cooking is a sequential and visually grounded activity, where each step such as chopping, mixing, or frying carries both procedural logic and visual semantics. While recent diffusion models have shown strong capabilities in text-to-image generation, they struggle to handle structured multi-step scenarios like recipe illustration. Additionally, current recipe illustration methods are unable to adjust to the natural variability in recipe length, generating a fixed number of images regardless of the actual instructions structure. To address these limitations, we present CookAnything, a flexible and consistent diffusion-based framework that generates coherent, semantically distinct image sequences from textual cooking instructions of arbitrary length. The framework introduces three key components: (1) Step-wise Regional Control (SRC), which aligns textual steps with corresponding image regions within a single denoising process; (2) Flexible RoPE, a step-aware positional encoding mechanism that enhances both temporal coherence and spatial diversity; and (3) Cross-Step Consistency Control (CSCC), which maintains fine-grained ingredient consistency across steps. Experimental results on recipe illustration benchmarks show that CookAnything performs better than existing methods in training-based and training-free settings. The proposed framework supports scalable, high-quality visual synthesis of complex multi-step instructions and holds significant potential for broad applications in instructional media, and procedural content creation.

The abundance of instructional videos and their narrations over the Internet offers an exciting avenue for understanding procedural activities. In this work, we propose to learn video representation that encodes both action steps and their temporal ordering, based on a large-scale dataset of web instructional videos and their narrations, without using human annotations. Our method jointly learns a video representation to encode individual step concepts, and a deep probabilistic model to capture both temporal dependencies and immense individual variations in the step ordering. We empirically demonstrate that learning temporal ordering not only enables new capabilities for procedure reasoning, but also reinforces the recognition of individual steps. Our model significantly advances the state-of-the-art results on step classification (+2.8% / +3.3% on COIN / EPIC-Kitchens) and step forecasting (+7.4% on COIN). Moreover, our model attains promising results in zero-shot inference for step classification and forecasting, as well as in predicting diverse and plausible steps for incomplete procedures. Our code is available at https://github.com/facebookresearch/ProcedureVRL.

Advanced models such as OpenAI o1 exhibit impressive problem-solving capabilities through step-by-step reasoning. However, they may still falter on more complex problems, making errors that disrupt their reasoning paths. We attribute this to the expansive solution space, where each step has the risk of diverging into mistakes. To enhance language model reasoning, we introduce a specialized training framework called Reasoning Paths Optimization (RPO), which enables learning to reason and explore from diverse paths. Our approach encourages favorable branches at each reasoning step while penalizing unfavorable ones, enhancing the model's overall problem-solving performance. Reasoning Paths Optimization does not rely on large-scale human-annotated rationales or outputs from closed-source models, making it scalable and data-efficient. We focus on multi-step reasoning tasks, such as math word problems and science-based exam questions. The experiments demonstrate that our framework significantly enhances the reasoning performance of large language models, with up to 3.1% and 4.3% improvement on GSM8K and MMLU (STEM) respectively. Our data and code can be found at https://reasoning-paths.github.io.

We study the problem of learning to perform multi-stage robotic manipulation tasks, with applications to cable routing, where the robot must route a cable through a series of clips. This setting presents challenges representative of complex multi-stage robotic manipulation scenarios: handling deformable objects, closing the loop on visual perception, and handling extended behaviors consisting of multiple steps that must be executed successfully to complete the entire task. In such settings, learning individual primitives for each stage that succeed with a high enough rate to perform a complete temporally extended task is impractical: if each stage must be completed successfully and has a non-negligible probability of failure, the likelihood of successful completion of the entire task becomes negligible. Therefore, successful controllers for such multi-stage tasks must be able to recover from failure and compensate for imperfections in low-level controllers by smartly choosing which controllers to trigger at any given time, retrying, or taking corrective action as needed. To this end, we describe an imitation learning system that uses vision-based policies trained from demonstrations at both the lower (motor control) and the upper (sequencing) level, present a system for instantiating this method to learn the cable routing task, and perform evaluations showing great performance in generalizing to very challenging clip placement variations. Supplementary videos, datasets, and code can be found at https://sites.google.com/view/cablerouting.

Leveraging multimodal large language models (MLLMs) to develop embodied agents offers significant promise for addressing complex real-world tasks. However, current evaluation benchmarks remain predominantly language-centric or heavily reliant on simulated environments, rarely probing the nuanced, knowledge-intensive reasoning essential for practical, real-world scenarios. To bridge this critical gap, we introduce the task of Sparsely Grounded Visual Navigation, explicitly designed to evaluate the sequential decision-making abilities of MLLMs in challenging, knowledge-intensive real-world environment. We operationalize this task with CityNav, a comprehensive benchmark encompassing four diverse global cities, specifically constructed to assess raw MLLM-driven agents in city navigation. Agents are required to rely solely on visual inputs and internal multimodal reasoning to sequentially navigate 50+ decision points without additional environmental annotations or specialized architectural modifications. Crucially, agents must autonomously achieve localization through interpreting city-specific cues and recognizing landmarks, perform spatial reasoning, and strategically plan and execute routes to their destinations. Through extensive evaluations, we demonstrate that current state-of-the-art MLLMs, reasoning techniques (e.g., GEPA, chain-of-thought, reflection) and competitive baseline PReP significantly underperform in this challenging setting. To address this, we propose Verbalization of Path(VoP), which explicitly grounds the agent's internal reasoning by probing city-scale cognitive maps (key landmarks and directions toward the destination) from the MLLM, substantially enhancing navigation success. Project Webpage: https://dwipddalal.github.io/AgentNav/

GUI grounding, which maps natural-language instructions to actionable UI elements, is a core capability of GUI agents. Prior works largely treats instructions as a static proxy for user intent, overlooking the impact of instruction diversity and quality on grounding performance. Through a careful investigation of existing grounding datasets, we find a 23.3% flaw rate in their instructions and show that inference-time exploitation of instruction diversity yields up to a substantial 76% relative performance improvement. In this paper, we introduce the Instruction-as-Reasoning paradigm, treating instructions as dynamic analytical pathways that offer distinct perspectives and enabling the model to select the most effective pathway during reasoning. To achieve this, we propose a two-stage training framework: supervised fine-tuning (SFT) on synthesized, diverse instructions to instill multi-perspective reasoning, followed by reinforcement learning (RL) to optimize pathway selection and composition. Our resulting models, UI-Ins-7B and UI-Ins-32B, achieve state-of-the-art results on five challenging grounding benchmarks and exhibit emergent reasoning, selectively composing and synthesizing novel instruction pathways at inference. In particular, UI-Ins-32B attains the best grounding accuracy, scoring 87.3% on UI-I2E-Bench, 57.0% on ScreenSpot-Pro, and 84.9% on MMBench-GUI L2. Furthermore, our model demonstrates strong agentic potential, achieving a 74.1% success rate on AndroidWorld using UI-Ins-7B as the executor. Our in-depth analysis reveals additional insights such as how reasoning can be formulated to enhance rather than hinder grounding performance, and how our method mitigates policy collapse in the SFT+RL framework. All code and model checkpoints will be publicly released in https://github.com/alibaba/UI-Ins.

This paper presents the second ChatGPT4PCG competition at the 2024 IEEE Conference on Games. In this edition of the competition, we follow the first edition, but make several improvements and changes. We introduce a new evaluation metric along with allowing a more flexible format for participants' submissions and making several improvements to the evaluation pipeline. Continuing from the first edition, we aim to foster and explore the realm of prompt engineering (PE) for procedural content generation (PCG). While the first competition saw success, it was hindered by various limitations; we aim to mitigate these limitations in this edition. We introduce diversity as a new metric to discourage submissions aimed at producing repetitive structures. Furthermore, we allow submission of a Python program instead of a prompt text file for greater flexibility in implementing advanced PE approaches, which may require control flow, including conditions and iterations. We also make several improvements to the evaluation pipeline with a better classifier for similarity evaluation and better-performing function signatures. We thoroughly evaluate the effectiveness of the new metric and the improved classifier. Additionally, we perform an ablation study to select a function signature to instruct ChatGPT for level generation. Finally, we provide implementation examples of various PE techniques in Python and evaluate their preliminary performance. We hope this competition serves as a resource and platform for learning about PE and PCG in general.

Recent work has shown that asking language models to generate reasoning steps improves performance on many reasoning tasks. When moving beyond prompting, this raises the question of how we should supervise such models: outcome-based approaches which supervise the final result, or process-based approaches which supervise the reasoning process itself? Differences between these approaches might naturally be expected not just in final-answer errors but also in reasoning errors, which can be difficult to detect and are problematic in many real-world domains such as education. We run the first comprehensive comparison between process- and outcome-based approaches trained on a natural language task, GSM8K. We find that pure outcome-based supervision produces similar final-answer error rates with less label supervision. However, for correct reasoning steps we find it necessary to use process-based supervision or supervision from learned reward models that emulate process-based feedback. In total, we improve the previous best results from 16.8% to 12.7% final-answer error and 14.0% to 3.4% reasoning error among final-answer-correct solutions.

End-to-end automation of realistic healthcare operations stresses three capabilities underrepresented in current benchmarks: policy density, decisions must be grounded in a large library of medical, insurance, and operational rules; Multi-role composition: a single task requires the agent to play multiple roles with handoffs; and multilateral interaction: intermediate workflow steps are multi-turn dialogs, such as peer-to-peer review and patient outreach. We introduce χ-Bench, a benchmark of long-horizon healthcare workflows across three domains: provider prior authorization, payer utilization management, and care management. Each task hands the agent a clinical case in a high-fidelity simulator of 20 healthcare apps exposed via 87 MCP tools, which it must drive to a terminal status through tool calls and writing the role's artifacts, guided by a 1,290+ document managed-care operations handbook skill. Across 30 agent harness/models configurations, the best agent resolves only 28.0% of tasks, no agent clears 20% on strict pass^3, and executing all tasks in a single session slumps the performance to 3.8%. These results raise the hypothesis that similar gaps are likely to surface in other policy-dense, role-composed, irreversible enterprise domains.

Problem: Effective patient-centered communication is a core competency for physicians. However, both seasoned providers and medical trainees report decreased confidence in leading conversations on sensitive topics such as goals of care or end-of-life discussions. The significant administrative burden and the resources required to provide dedicated training in leading difficult conversations has been a long-standing problem in medical education. Approach: In this work, we present a novel educational tool designed to facilitate interactive, real-time simulations of difficult conversations in a video-based format through the use of multimodal generative artificial intelligence (AI). Leveraging recent advances in language modeling, computer vision, and generative audio, this tool creates realistic, interactive scenarios with avatars, or "synthetic patients." These synthetic patients interact with users throughout various stages of medical care using a custom-built video chat application, offering learners the chance to practice conversations with patients from diverse belief systems, personalities, and ethnic backgrounds. Outcomes: While the development of this platform demanded substantial upfront investment in labor, it offers a highly-realistic simulation experience with minimal financial investment. For medical trainees, this educational tool can be implemented within programs to simulate patient-provider conversations and can be incorporated into existing palliative care curriculum to provide a scalable, high-fidelity simulation environment for mastering difficult conversations. Next Steps: Future developments will explore enhancing the authenticity of these encounters by working with patients to incorporate their histories and personalities, as well as employing the use of AI-generated evaluations to offer immediate, constructive feedback to learners post-simulation.

In recent years, cancer genome sequencing and other high-throughput studies of cancer genomes have generated many notable discoveries. In this review, Novel genomic alteration mechanisms, such as chromothripsis (chromosomal crisis) and kataegis (mutation storms), and their implications for cancer are discussed. Genomic alterations spur cancer genome evolution. Thus, the relationship between cancer clonal evolution and cancer stems cells is commented. The key question in cancer biology concerns how these genomic alterations support cancer development and metastasis in the context of biological functioning. Thus far, efforts such as pathway analysis have improved the understanding of the functional contributions of genetic mutations and DNA copy number variations to cancer development, progression and metastasis. However, the known pathways correspond to a small fraction, plausibly 5-10%, of somatic mutations and genes with an altered copy number. To develop a comprehensive understanding of the function of these genomic alterations in cancer, an integrative network framework is proposed and discussed. Finally, the challenges and the directions of studying cancer omic data using an integrative network approach are commented.

For many segmentation tasks, especially for the biomedical image, the topological prior is vital information which is useful to exploit. The containment/nesting is a typical inter-class geometric relationship. In the MICCAI Brain tumor segmentation challenge, with its three hierarchically nested classes 'whole tumor', 'tumor core', 'active tumor', the nested classes relationship is introduced into the 3D-residual-Unet architecture. The network comprises a context aggregation pathway and a localization pathway, which encodes increasingly abstract representation of the input as going deeper into the network, and then recombines these representations with shallower features to precisely localize the interest domain via a localization path. The nested-class-prior is combined by proposing the multi-class activation function and its corresponding loss function. The model is trained on the training dataset of Brats2018, and 20% of the dataset is regarded as the validation dataset to determine parameters. When the parameters are fixed, we retrain the model on the whole training dataset. The performance achieved on the validation leaderboard is 86%, 77% and 72% Dice scores for the whole tumor, enhancing tumor and tumor core classes without relying on ensembles or complicated post-processing steps. Based on the same start-of-the-art network architecture, the accuracy of nested-class (enhancing tumor) is reasonably improved from 69% to 72% compared with the traditional Softmax-based method which blind to topological prior.

The emergence of tool-calling-based agent systems introduces a more evidence-driven paradigm for pathology image analysis in contrast to the coarse-grained text-image diagnostic approaches. With the recent large-scale experimental adoption of spatial transcriptomics technologies, molecularly validated pathological diagnosis is becoming increasingly open and accessible. In this work, we propose LAMMI-Pathology (LVLM-Agent System for Molecularly Informed Medical Intelligence in Pathology), a scalable agent framework for domain-specific agent tool-calling. LAMMI-Pathology adopts a tool-centric, bottom-up architecture in which customized domain-adaptive tools serve as the foundation. These tools are clustered by domain style to form component agents, which are then coordinated through a top-level planner hierarchically, avoiding excessively long context lengths that could induce task drift. Based on that, we introduce a novel trajectory construction mechanism based on Atomic Execution Nodes (AENs), which serve as reliable and composable units for building semi-simulated reasoning trajectories that capture credible agent-tool interactions. Building on this foundation, we develop a trajectory-aware fine-tuning strategy that aligns the planner's decision-making process with these multi-step reasoning trajectories, thereby enhancing inference robustness in pathology understanding and its adaptive use of the customized toolset.

We formulate a hierarchical rectified flow to model data distributions. It hierarchically couples multiple ordinary differential equations (ODEs) and defines a time-differentiable stochastic process that generates a data distribution from a known source distribution. Each ODE resembles the ODE that is solved in a classic rectified flow, but differs in its domain, i.e., location, velocity, acceleration, etc. Unlike the classic rectified flow formulation, which formulates a single ODE in the location domain and only captures the expected velocity field (sufficient to capture a multi-modal data distribution), the hierarchical rectified flow formulation models the multi-modal random velocity field, acceleration field, etc., in their entirety. This more faithful modeling of the random velocity field enables integration paths to intersect when the underlying ODE is solved during data generation. Intersecting paths in turn lead to integration trajectories that are more straight than those obtained in the classic rectified flow formulation, where integration paths cannot intersect. This leads to modeling of data distributions with fewer neural function evaluations. We empirically verify this on synthetic 1D and 2D data as well as MNIST, CIFAR-10, and ImageNet-32 data. Our code is available at: https://riccizz.github.io/HRF/.

This document serves as a position paper that outlines the authors' vision for a potential pathway towards generalist robots. The purpose of this document is to share the excitement of the authors with the community and highlight a promising research direction in robotics and AI. The authors believe the proposed paradigm is a feasible path towards accomplishing the long-standing goal of robotics research: deploying robots, or embodied AI agents more broadly, in various non-factory real-world settings to perform diverse tasks. This document presents a specific idea for mining knowledge in the latest large-scale foundation models for robotics research. Instead of directly using or adapting these models to produce low-level policies and actions, it advocates for a fully automated generative pipeline (termed as generative simulation), which uses these models to generate diversified tasks, scenes and training supervisions at scale, thereby scaling up low-level skill learning and ultimately leading to a foundation model for robotics that empowers generalist robots. The authors are actively pursuing this direction, but in the meantime, they recognize that the ambitious goal of building generalist robots with large-scale policy training demands significant resources such as computing power and hardware, and research groups in academia alone may face severe resource constraints in implementing the entire vision. Therefore, the authors believe sharing their thoughts at this early stage could foster discussions, attract interest towards the proposed pathway and related topics from industry groups, and potentially spur significant technical advancements in the field.

In this study, we present Colon-X, an open initiative aimed at advancing multimodal intelligence in colonoscopy. We begin by constructing ColonVQA, the most comprehensive multimodal dataset ever built for colonoscopy, featuring over 1.1M+ visual question answering entries across 76 clinical findings and 18 multimodal tasks. Beyond serving as a community-wide data foundation, we further investigate a critical yet underexplored transition in colonoscopy - evolving from multimodal understanding to clinical reasoning: (a) To capture the current landscape of multimodal understanding behaviors, we systematically assess the generalizability of 22 multimodal large language models and examine their reliability under human-induced perturbations. The results reveal that clinical outputs from leading MLLMs remain far from robust and trustworthy. (b) To narrow this gap, we further explore reasoning-centric intelligence tailored for colonoscopy. Specifically, we curate ColonReason, a clinically grounded reasoning dataset annotated through a multi-expert debating pipeline, and develop ColonR1, the first R1-styled model incorporating task-adaptive rewarding and gradient-stable optimization techniques. Under data-scarce conditions, our ColonR1 achieves 56.61% overall accuracy, outperforming supervised fine-tuning by 25.22%, and sets a new reasoning-enabled baseline for multimodal colonoscopy analysis. All data and model resources are publicly available at https://github.com/ai4colonoscopy/Colon-X.

Learning how to do things from trial and error in real time is a hallmark of biological intelligence, yet most LLM-based agents lack mechanisms to acquire procedural knowledge after deployment. We propose Procedural Recall for Agents with eXperiences Indexed by State (PRAXIS), a lightweight post-training learning mechanism that stores the consequences of actions and retrieves them by jointly matching environmental and internal states of past episodes to the current state. PRAXIS augments agentic action selection with retrieved state-action-result exemplars that are generated in real time. When evaluated on the REAL web browsing benchmark, PRAXIS improves task completion accuracy, reliability, and cost efficiency across different foundation model backbones, and shows preliminary generalization to unseen tasks in similar environments. These results demonstrate that PRAXIS enables the practical adoption of AI agents in fast-evolving stateful environments by helping them learn new procedures effectively.

Flowcharts are a critical tool for visualizing decision-making processes. However, their non-linear structure and complex visual-textual relationships make it challenging to interpret them using LLMs, as vision-language models frequently hallucinate nonexistent connections and decision paths when analyzing these diagrams. This leads to compromised reliability for automated flowchart processing in critical domains such as logistics, health, and engineering. We introduce the task of Fine-grained Flowchart Attribution, which traces specific components grounding a flowchart referring LLM response. Flowchart Attribution ensures the verifiability of LLM predictions and improves explainability by linking generated responses to the flowchart's structure. We propose FlowPathAgent, a neurosymbolic agent that performs fine-grained post hoc attribution through graph-based reasoning. It first segments the flowchart, then converts it into a structured symbolic graph, and then employs an agentic approach to dynamically interact with the graph, to generate attribution paths. Additionally, we present FlowExplainBench, a novel benchmark for evaluating flowchart attributions across diverse styles, domains, and question types. Experimental results show that FlowPathAgent mitigates visual hallucinations in LLM answers over flowchart QA, outperforming strong baselines by 10-14% on our proposed FlowExplainBench dataset.

Agentic systems increasingly rely on reusable procedural capabilities, a.k.a., agentic skills, to execute long-horizon workflows reliably. These capabilities are callable modules that package procedural knowledge with explicit applicability conditions, execution policies, termination criteria, and reusable interfaces. Unlike one-off plans or atomic tool calls, skills operate (and often do well) across tasks. This paper maps the skill layer across the full lifecycle (discovery, practice, distillation, storage, composition, evaluation, and update) and introduces two complementary taxonomies. The first is a system-level set of seven design patterns capturing how skills are packaged and executed in practice, from metadata-driven progressive disclosure and executable code skills to self-evolving libraries and marketplace distribution. The second is an orthogonal representation times scope taxonomy describing what skills are (natural language, code, policy, hybrid) and what environments they operate over (web, OS, software engineering, robotics). We analyze the security and governance implications of skill-based agents, covering supply-chain risks, prompt injection via skill payloads, and trust-tiered execution, grounded by a case study of the ClawHavoc campaign in which nearly 1{,}200 malicious skills infiltrated a major agent marketplace, exfiltrating API keys, cryptocurrency wallets, and browser credentials at scale. We further survey deterministic evaluation approaches, anchored by recent benchmark evidence that curated skills can substantially improve agent success rates while self-generated skills may degrade them. We conclude with open challenges toward robust, verifiable, and certifiable skills for real-world autonomous agents.

The production of 2D animation follows an industry-standard workflow, encompassing four essential stages: character design, keyframe animation, in-betweening, and coloring. Our research focuses on reducing the labor costs in the above process by harnessing the potential of increasingly powerful generative AI. Using video diffusion models as the foundation, AniDoc emerges as a video line art colorization tool, which automatically converts sketch sequences into colored animations following the reference character specification. Our model exploits correspondence matching as an explicit guidance, yielding strong robustness to the variations (e.g., posture) between the reference character and each line art frame. In addition, our model could even automate the in-betweening process, such that users can easily create a temporally consistent animation by simply providing a character image as well as the start and end sketches. Our code is available at: https://yihao-meng.github.io/AniDoc_demo.

Large language model (LLM) agents accumulate rich episodic trajectories while solving real-world tasks, but it remains unclear whether such experience can be distilled into reusable procedural skills. We introduce SkillEvolBench, a diagnostic benchmark for evaluating this step from experience reuse to skill formation. It contains 180 tasks across six real-world agent environments, organized into role-conditioned task families with shared latent procedures. Agents learn from acquisition tasks, update an external skill library using compacted trajectories and verifier feedback, and then face frozen deployment tasks testing context shift, adversarial shortcuts, and composition. By comparing self-generated and curated-start skill evolution against no-skill and raw-trajectory controls, SkillEvolBench separates procedural abstraction from base capability, curated prior knowledge, and direct reuse of episodic traces. Across ten model configurations and three agent harnesses, we find that current agents often adapt locally but rarely form robust reusable skills. Skill-based conditions can improve acquisition or replay, and individual models sometimes gain on specific deployment axes, but these gains are unstable under frozen deployment. Raw-trajectory reuse frequently outperforms distilled skills, suggesting that current abstraction procedures discard contextual and procedural cues that remain useful for future tasks. Capacity and cost analyses further show that writing more skills or larger Tier-3 resource libraries is not sufficient: additional updates can improve coverage while introducing episode-specific drift and procedural clutter. These findings position SkillEvolBench as a testbed for measuring when one-off experience becomes durable procedural knowledge rather than task-local memory.

PURPOSE: Surgical workflow and skill analysis are key technologies for the next generation of cognitive surgical assistance systems. These systems could increase the safety of the operation through context-sensitive warnings and semi-autonomous robotic assistance or improve training of surgeons via data-driven feedback. In surgical workflow analysis up to 91% average precision has been reported for phase recognition on an open data single-center dataset. In this work we investigated the generalizability of phase recognition algorithms in a multi-center setting including more difficult recognition tasks such as surgical action and surgical skill. METHODS: To achieve this goal, a dataset with 33 laparoscopic cholecystectomy videos from three surgical centers with a total operation time of 22 hours was created. Labels included annotation of seven surgical phases with 250 phase transitions, 5514 occurences of four surgical actions, 6980 occurences of 21 surgical instruments from seven instrument categories and 495 skill classifications in five skill dimensions. The dataset was used in the 2019 Endoscopic Vision challenge, sub-challenge for surgical workflow and skill analysis. Here, 12 teams submitted their machine learning algorithms for recognition of phase, action, instrument and/or skill assessment. RESULTS: F1-scores were achieved for phase recognition between 23.9% and 67.7% (n=9 teams), for instrument presence detection between 38.5% and 63.8% (n=8 teams), but for action recognition only between 21.8% and 23.3% (n=5 teams). The average absolute error for skill assessment was 0.78 (n=1 team). CONCLUSION: Surgical workflow and skill analysis are promising technologies to support the surgical team, but are not solved yet, as shown by our comparison of algorithms. This novel benchmark can be used for comparable evaluation and validation of future work.

The objective is the design of a Cellular Automata rule that can form patterns with 'touching' loops. A loop is defined as a closed path of 1-cells in a 2D grid on a zero background and with a zero border. A path cell is connected with two of its adjacent neighbors. In touching loops a path cell is also allowed to touch another on a diagonal. A CA rule was designed that can evolve stable touching loop patterns. The rule tries to cover the 2D space by overlapping tiles. The rule uses so-called templates, 5 x 5 matching patterns which are systematically derived from the given set of 3 x 3 tiles. The rule checks the pattern being evolved against a list of templates. If the outer neighbors of a template match, then the cell's state is set to the template's center value. Noise is injected if there is no matching template, or the tiles are not properly assembled. Thereby the evolution is driven to the desired loop patterns.

Gastrointestinal malignancies constitute a leading cause of cancer-related mortality worldwide, with advanced-stage prognosis remaining particularly dismal. Originating as a groundbreaking technique for early gastric cancer treatment, Endoscopic Submucosal Dissection has evolved into a versatile intervention for diverse gastrointestinal lesions. While computer-assisted systems significantly enhance procedural precision and safety in ESD, their clinical adoption faces a critical bottleneck: reliable surgical phase recognition within complex endoscopic workflows. Current state-of-the-art approaches predominantly rely on multi-stage refinement architectures that iteratively optimize temporal predictions. In this paper, we present Clinical Prior Knowledge-Constrained Diffusion (CPKD), a novel generative framework that reimagines phase recognition through denoising diffusion principles while preserving the core iterative refinement philosophy. This architecture progressively reconstructs phase sequences starting from random noise and conditioned on visual-temporal features. To better capture three domain-specific characteristics, including positional priors, boundary ambiguity, and relation dependency, we design a conditional masking strategy. Furthermore, we incorporate clinical prior knowledge into the model training to improve its ability to correct phase logical errors. Comprehensive evaluations on ESD820, Cholec80, and external multi-center demonstrate that our proposed CPKD achieves superior or comparable performance to state-of-the-art approaches, validating the effectiveness of diffusion-based generative paradigms for surgical phase recognition.

Outcome-reward reinforcement learning (RL) has proven effective at improving the reasoning capabilities of large language models (LLMs). However, standard RL assigns credit only at the level of the final answer, penalizing entire reasoning traces when the outcome is incorrect and uniformly reinforcing all steps when it is correct. As a result, correct intermediate steps may be discouraged in failed traces, while spurious steps may be reinforced in successful ones. We refer to this failure mode as the problem of credit assignment. While a natural remedy is to train a process reward model, accurately optimizing such models to identify corrective reasoning steps remains challenging. We introduce Intervention Training (InT), a training paradigm in which the model performs fine-grained credit assignment on its own reasoning traces by proposing short, targeted corrections that steer trajectories toward higher reward. Using reference solutions commonly available in mathematical reasoning datasets and exploiting the fact that verifying a model-generated solution is easier than generating a correct one from scratch, the model identifies the first error in its reasoning and proposes a single-step intervention to redirect the trajectory toward the correct solution. We then apply supervised fine-tuning (SFT) to the on-policy rollout up to the point of error concatenated with the intervention, localizing error to the specific step that caused failure. We show that the resulting model serves as a far better initialization for RL training. After running InT and subsequent fine-tuning with RL, we improve accuracy by nearly 14% over a 4B-parameter base model on IMO-AnswerBench, outperforming larger open-source models such as gpt-oss-20b.

3D Scene Graphs integrate both metric and semantic information, yet their structure remains underutilized for improving path planning efficiency and interpretability. In this work, we present S-Path, a situationally-aware path planner that leverages the metric-semantic structure of indoor 3D Scene Graphs to significantly enhance planning efficiency. S-Path follows a two-stage process: it first performs a search over a semantic graph derived from the scene graph to yield a human-understandable high-level path. This also identifies relevant regions for planning, which later allows the decomposition of the problem into smaller, independent subproblems that can be solved in parallel. We also introduce a replanning mechanism that, in the event of an infeasible path, reuses information from previously solved subproblems to update semantic heuristics and prioritize reuse to further improve the efficiency of future planning attempts. Extensive experiments on both real-world and simulated environments show that S-Path achieves average reductions of 5.7x in planning time while maintaining comparable path optimality to classical sampling-based planners and surpassing them in complex scenarios, making it an efficient and interpretable path planner for environments represented by indoor 3D Scene Graphs.